Brief Information of the Compound and Protein
Compound Name
3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide
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PubChem ID
CID: 44335885
Canonical SMILES
CNS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(C)c4ccc(OC)cc34)c2c1
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Compound Formula C20H19N3O4S
Compound Structure
Protein Name
BDNF/NT-3 growth factors receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
Q16620
Gene Name
NTRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000452 MG87 Mus musculus (Mouse)  1
1
IC50 = 41.07 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.52 nM