Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(6-(1-acryloylpiperidin-4-yl)pyridin-3-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide
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 PubChem ID
CID: 139558755
Canonical SMILES
C=CC(=O)N1CCC(c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cn2)CC1
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Compound Formula C22H27N5O2
Compound Structure
Protein Name
 Protein Info 
Cyclin-dependent kinase 12
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
Uniprot ID
Q9NYV4
Gene Name
CDK12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd < 25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 58 nM