Brief Information of the Compound and Protein
Compound Name
4-[4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]thieno[3,2-d]pyrimidin-2-yl]amino]phenyl]piperazine-1-sulfonamide
    Show/Hide
Canonical SMILES
Cc1cc(\C=C\C#N)cc(C)c1Oc1nc(Nc2ccc(cc2)N2CCN(CC2)S(N)(=O)=O)nc2ccsc12
    Show/Hide
Compound Formula C27H27N7O3S2
Compound Structure
Protein Name
Reverse transcriptase
Protein Classification
Enzyme
Uniprot ID
Q9WKE8
Gene Name
REVERSE TRANSCRIPTASE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  5
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
2
EC50 = 43 nM
   TI
   LI
   LO
   TS
3
EC50 = 203 nM
   TI
   LI
   LO
   TS
4
EC50 = 767 nM
   TI
   LI
   LO
   TS
5
EC50 = 23110 nM
   TI
   LI
   LO
   TS