Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-[3,5-dimethyl-4-[2-[4-(4-methylsulfonylpiperazin-1-yl)anilino]thieno[2,3-d]pyrimidin-4-yl]oxyphenyl]prop-2-enenitrile
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Canonical SMILES
Cc1cc(\C=C\C#N)cc(C)c1Oc1nc(Nc2ccc(cc2)N2CCN(CC2)S(C)(=O)=O)nc2sccc12
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Compound Formula C28H28N6O3S2
Compound Structure
Protein Name
 Protein Info 
Reverse transcriptase
Protein Classification
Enzyme
Uniprot ID
Q9WKE8
Gene Name
REVERSE TRANSCRIPTASE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 219 nM
   TI
   LI
   LO
   TS
2
EC50 = 405 nM
   TI
   LI
   LO
   TS
3
EC50 = 1952 nM
   TI
   LI
   LO
   TS
4
EC50 = 3322 nM
   TI
   LI
   LO
   TS
5
EC50 = 68430 nM
   TI
   LI
   LO
   TS