Brief Information of the Compound and Protein
Compound Name
N-[1-[4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]thieno[3,2-d]pyrimidin-2-yl]amino]phenyl]piperidin-3-yl]methanesulfonamide
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Canonical SMILES
Cc1cc(\C=C\C#N)cc(C)c1Oc1nc(Nc2ccc(cc2)N2CCCC(C2)NS(C)(=O)=O)nc2ccsc12
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Compound Formula C29H30N6O3S2
Compound Structure
Protein Name
Reverse transcriptase
Protein Classification
Enzyme
Uniprot ID
Q9WKE8
Gene Name
REVERSE TRANSCRIPTASE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  4
1
EC50 = 461 nM
   TI
   LI
   LO
   TS
2
EC50 = 1285 nM
   TI
   LI
   LO
   TS
3
EC50 = 6823 nM
   TI
   LI
   LO
   TS
4
EC50 = 16780 nM
   TI
   LI
   LO
   TS