Brief Information of the Compound and Protein
Compound Name
11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2 ,3 -e][1,4]diazepin-6-one
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PubChem ID
CID: 4463
SID: 14872507
Canonical SMILES
Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12
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Compound Formula C15H14N4O
Compound Structure
Protein Name
Reverse transcriptase
Protein Classification
Enzyme
Uniprot ID
Q9WKE8
Gene Name
REVERSE TRANSCRIPTASE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  9
1
EC50 = 168 nM
   TI
   LI
   LO
   TS
2
EC50 = 622 nM
   TI
   LI
   LO
   TS
3
EC50 = 1201.7 nM
   TI
   LI
   LO
   TS
4
EC50 = 3154.3 nM
   TI
   LI
   LO
   TS
5
EC50 = 3922 nM
   TI
   LI
   LO
   TS
6
EC50 = 4694 nM
   TI
   LI
   LO
   TS
7
EC50 = 6496.4 nM
   TI
   LI
   LO
   TS
8
EC50 = 8041 nM
   TI
   LI
   LO
   TS
9
EC50 = 9074 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 860 nM
2 IC50 = 7130 nM
3 IC50 = 67600 nM