Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(1S)-1-Cyclopropylethyl]-6-[3-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-3-oxo-2,3-dihydro-1H-isoindole-4-carbonitrile
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Canonical SMILES
C[C@@H](C1CC1)N1Cc2cc(-c3cnc4[nH]cc(-c5cnn(C)c5)c4c3)cc(C#N)c2C1=O
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Compound Formula C25H22N6O
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.7 nM