Brief Information of the Compound and Protein
Compound Name
rac-2-(1-Cyclopropylethyl)-7-methyl-5-[3-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-2,3-dihydro-1H-isoindol-1-one
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Canonical SMILES
Cc1cc(-c2cnc3[nH]cc(-c4cccnc4)c3c2)cc2c1C(=O)N(C(C)C1CC1)C2
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Compound Formula C26H24N4O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM