Brief Information of the Compound and Protein
Compound Name
2-[(1S)-1-Cyclopropylethyl]-5-{3-[6-(2-hydroxypropan-2-yl)pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-7-methyl-2,3-dihydro-1H-isoindol-1-one
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Canonical SMILES
Cc1cc(-c2cnc3[nH]cc(-c4ccc(C(C)(C)O)nc4)c3c2)cc2c1C(=O)N([C@@H](C)C1CC1)C2
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Compound Formula C29H30N4O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.3 nM