Brief Information of the Compound and Protein
Compound Name
2-(dicyclopropylmethyl)-7-methyl-5-(3-pyridin-4-yl-1H-pyrrolo[2,3-b]pyridin-5-yl)-3H-isoindol-1-one
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Canonical SMILES
Cc1cc(cc2CN(C(C3CC3)C3CC3)C(=O)c12)-c1cnc2[nH]cc(-c3ccncc3)c2c1
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Compound Formula C28H26N4O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.8 nM