Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1S,2R)-2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]cyclopentyl]prop-2-enamide
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Canonical SMILES
COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(N[C@@H]3CCC[C@@H]3NC(=O)C=C)nc2n(C)c1=O
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Compound Formula C24H25Cl2N5O4
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P21802
Gene Name
FGFR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000432 KATO III
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 359 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 247 nM