Brief Information of the Compound and Protein
Compound Name
N-(6-methyl-2-phenylpyrimidin-4-yl)quinolin-6-amine
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Canonical SMILES
Cc1cc(Nc2ccc3ncccc3c2)nc(n1)-c1ccccc1
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Compound Formula C20H16N4
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  2
1
EC50 = 8410 nM
   TI
   LI
   LO
   TS
2
IC50 = 5130 nM
   TI
   LI
   LO
   TS