Brief Information of the Compound and Protein
Compound Name
N-(4-bromo-3-methoxyphenyl)-6-methyl-2-phenylpyrimidin-4-amine
    Show/Hide
Canonical SMILES
COc1cc(Nc2cc(C)nc(n2)-c2ccccc2)ccc1Br
    Show/Hide
Compound Formula C18H16BrN3O
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 5030 nM
   TI
   LI
   LO
   TS