Brief Information of the Compound and Protein
Compound Name
6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]indazole-5-carbonitrile
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PubChem ID
CID: 155817684
Canonical SMILES
CN1CCN(CC1)c1ccc(cc1)-n1ncc2cc(C#N)c(cc12)-c1c(C)cccc1F
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Compound Formula C26H24FN5
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase KHS subfamily
Uniprot ID
Q92918
Gene Name
MAP4K1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 10000 nM