Brief Information of the Compound and Protein
Compound Name
3-[1-[2-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]pyridin-4-yl]indazol-6-yl]-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine
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Canonical SMILES
C[C@H]1CN(C[C@@H](C)N1C)c1cc(ccn1)-n1ncc2ccc(cc12)-c1cnn2CCCOc12
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Compound Formula C25H29N7O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 1
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
STE protein kinase group
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STE protein kinase STE20 family
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STE protein kinase KHS subfamily
Uniprot ID
Q92918
Gene Name
MAP4K1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1460 nM
   TI
   LI
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   TS