Brief Information of the Compound and Protein
Compound Name
6-(2-fluoro-6-methoxyphenyl)-1-[6-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)pyridin-2-yl]pyrazolo[4,3-c]pyridine
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Canonical SMILES
COc1cccc(F)c1-c1cc2n(ncc2cn1)-c1cccc(n1)N1CC2CCC(C1)N2C
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Compound Formula C25H25FN6O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase KHS subfamily
Uniprot ID
Q92918
Gene Name
MAP4K1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4000 nM