Brief Information of the Compound and Protein
Compound Name
N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-7-formyl-6-[(4-methyl-3-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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Canonical SMILES
COCCOc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)C(=O)C4)c(C=O)nc23)ncc1C#N
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Compound Formula C25H29N7O5
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS
2
Kd = 3.5 nM
   TI
   LI
   LO
   TS