Brief Information of the Compound and Protein
Compound Name
US9266883, 1
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PubChem ID
CID: 118036250
Canonical SMILES
FC(F)(F)c1ccc(NC(=O)N2CCCc3ccc(C=O)nc23)nc1
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Compound Formula C16H13F3N4O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
Kd = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM
2 IC50 > 10000 nM