Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2R,3R,4S,5R,6S)-4-acetamido-2-amino-3-[(4-fluoro-3-methylphenyl)sulfanylmethyl]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid;hydrochloride
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Canonical SMILES
Cl.CC(=O)N[C@H]1[C@H]2[C@@H]([C@H]2[C@@](N)([C@@H]1CSc1ccc(F)c(C)c1)C(O)=O)C(O)=O
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Compound Formula C18H22ClFN2O5S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
IC50 = 26.2 nM
   TI
   LI
   LO
   TS