Brief Information of the Compound and Protein
Compound Name
(1S,2R,3S,4S,5R,6R)-2-amino-3-[(3,4-dichlorophenyl)methylsulfanylmethyl]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid;hydrochloride
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Canonical SMILES
Cl.N[C@@]1([C@H]2[C@H]([C@@H]2C(O)=O)[C@H](O)[C@H]1CSCc1ccc(Cl)c(Cl)c1)C(O)=O
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Compound Formula C16H18Cl3NO5S
Compound Structure
Protein Name
Metabotropic glutamate receptor 3
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14832
Gene Name
GRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901 Mesocricetus auratus (Golden hamster)  1
1
IC50 = 62.3 nM
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