Brief Information of the Compound and Protein
Compound Name
6-(1,3-dimethylpyrazol-4-yl)-3-[(1R)-1-quinolin-6-ylethyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
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PubChem ID
CID: 49821917
SID: 103804383
Canonical SMILES
C[C@@H](c1nnc2sc(nn12)-c1cn(C)nc1C)c1ccc2ncccc2c1
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Compound Formula C19H17N7S
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000267 SNU-5 Homo sapiens (Human)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 24 nM