Brief Information of the Compound and Protein
Compound Name
4-[[6-(4-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl]methyl]phenol
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Canonical SMILES
Oc1ccc(Cc2nnc3SCC(=Nn23)c2ccc(F)cc2)cc1
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Compound Formula C17H13FN4OS
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000267 SNU-5 Homo sapiens (Human)  1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 80 nM