Brief Information of the Compound and Protein
Compound Name
4-[[6-(2-hydroxyanilino)-2-phenylpyrimidin-4-yl]amino]benzonitrile
    Show/Hide
Canonical SMILES
Oc1ccccc1Nc1cc(Nc2ccc(cc2)C#N)nc(n1)-c1ccccc1
    Show/Hide
Compound Formula C23H17N5O
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  2
1
EC50 = 34400 nM
   TI
   LI
   LO
   TS
2
IC50 = 2980 nM
   TI
   LI
   LO
   TS