Brief Information of the Compound and Protein
Compound Name
4-[[2-phenyl-6-(propan-2-ylamino)pyrimidin-4-yl]amino]benzonitrile
    Show/Hide
PubChem ID
CID: 112879416
Canonical SMILES
CC(C)Nc1cc(Nc2ccc(cc2)C#N)nc(n1)-c1ccccc1
    Show/Hide
Compound Formula C20H19N5
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 6420 nM
   TI
   LI
   LO
   TS