Brief Information of the Compound and Protein
Compound Name
2-methyl-4-(4-methylpiperazin-1-yl)-6-[[methyl(5,6,7,8-tetrahydroquinolin-8-yl)amino]methyl]pyrimidine-5-carbonitrile
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PubChem ID
CID: 138501659
Canonical SMILES
CN(Cc1nc(C)nc(N2CCN(C)CC2)c1C#N)C1CCCc2cccnc12
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Compound Formula C22H29N7
Compound Structure
Protein Name
C-X-C chemokine receptor type 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P61073
Gene Name
CXCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000571 HPB-ALL Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS