Brief Information of the Compound and Protein
Compound Name
(8S)-N-[[6-[(2R)-2,4-dimethylpiperazin-1-yl]-2-methylpyrimidin-4-yl]methyl]-N-methyl-5,6,7,8-tetrahydroquinolin-8-amine
    Show/Hide
PubChem ID
CID: 138501644
Canonical SMILES
C[C@@H]1CN(C)CCN1c1cc(CN(C)[C@H]2CCCc3cccnc23)nc(C)n1
    Show/Hide
Compound Formula C22H32N6
Compound Structure
Protein Name
C-X-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P61073
Gene Name
CXCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000571 HPB-ALL Homo sapiens (Human)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS