Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-(2-(1H-indol-3-yl)-2-oxoacetamido)-N4-tert-butyl-N1-((S)-1-(naphthalen-1-ylmethylamino)-1-oxopropan-2-yl)succinamide
    Show/Hide
 PubChem ID
CID: 118234443
Canonical SMILES
C[C@H](NC(=O)[C@H](CC(=O)NC(C)(C)C)NC(=O)C(=O)c1c[nH]c2ccccc12)C(=O)NCc1cccc2ccccc12
    Show/Hide
Compound Formula C32H35N5O5
Compound Structure
Protein Name
 Protein Info 
Proteasome subunit beta type-8
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28062
Gene Name
PSMB8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000626 Karpas-1106P
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM