Brief Information of the Compound and Protein
Compound Name
 Compound Info 
PULRODEMSTAT BESILATE
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 PubChem ID
CID: 129096972
Canonical SMILES
COc1ccc(-c2c(-c3ccc(C#N)c(F)c3)nc(N3CCC(N)CC3)n(C)c2=O)cc1F.O=S(=O)(O)c1ccccc1
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Compound Formula C30H29F2N5O5S
Compound Structure
Protein Name
 Protein Info 
Lysine-specific histone demethylase 1A
Protein Classification
Epigenetic regulator
>
Eraser
>
Lysine demethylase
>
Lysine-specific demethylase
Uniprot ID
O60341
Gene Name
KDM1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000734 NCI-H1417
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
2
EC50 = 6 nM
   TI
   LI
   LO
   TS
CL000358 NCI-H69
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.3 nM