Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[2-[(3aR,7aS)-1,2,3,3a,4,6,7,7a-octahydropyrrolo[3,2-c]pyridin-5-yl]-5-(4-methylphenyl)pyrimidin-4-yl]benzonitrile
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Canonical SMILES
Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CC[C@@H]2NCC[C@@H]2C1
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Compound Formula C25H25N5
Compound Structure
Protein Name
 Protein Info 
Lysine-specific histone demethylase 1A
Protein Classification
Epigenetic regulator
>
Eraser
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Lysine demethylase
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Lysine-specific demethylase
Uniprot ID
O60341
Gene Name
KDM1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 73 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.4 nM