Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-(4-amino-piperidin-1-yl)-4- methyl-5-oxo-3-p-tolyl-4,5- dihydro-pyrazin-2-yl]-2-fluoro- benzonitrile
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 PubChem ID
CID: 118610149
Canonical SMILES
Cc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)c(=O)n1C)-c1ccc(C#N)c(F)c1
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Compound Formula C24H24FN5O
Compound Structure
Protein Name
 Protein Info 
Lysine-specific histone demethylase 1A
Protein Classification
Epigenetic regulator
>
Eraser
>
Lysine demethylase
>
Lysine-specific demethylase
Uniprot ID
O60341
Gene Name
KDM1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5 nM