Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5Z)-5-[(3-chloro-4-hydroxyphenyl)methylidene]-2-(3,3-difluorocyclobutyl)imino-3-(2-methylphenyl)-1,3-thiazolidin-4-one
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Canonical SMILES
Cc1ccccc1N1C(=O)\C(S\C1=N/C1CC(F)(F)C1)=C\c1ccc(O)c(Cl)c1
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Compound Formula C21H17ClF2N2O2S
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000436 PathHunter CHO-K1 EDG1 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 199.53 nM
   TI
   LI
   LO
   TS