Brief Information of the Compound and Protein
Compound Name
(5Z)-5-[(3-chloro-4-hydroxyphenyl)methylidene]-2-(2-methoxyethylimino)-3-(2-methylphenyl)-1,3-thiazolidin-4-one
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Canonical SMILES
COCC\N=C1/S\C(=C/c2ccc(O)c(Cl)c2)C(=O)N1c1ccccc1C
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Compound Formula C20H19ClN2O3S
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000436 PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster)  1
1
IC50 = 501.19 nM
   TI
   LI
   LO
   TS