Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CPI-455
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Canonical SMILES
CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1
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Compound Formula C16H14N4O
Compound Structure
Protein Name
 Protein Info 
Lysine-specific demethylase 5B
Protein Classification
Epigenetic regulator
>
Eraser
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Lysine demethylase
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Jumonji domain-containing
Uniprot ID
Q9UGL1
Gene Name
KDM5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 10.52 nM
   TI
   LI
   LO
   TS
2
IC50 = 337 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM
2 IC50 = 10 nM