Brief Information of the Compound and Protein
Compound Name
2-[7-[1-(2,2-difluoroethyl)azetidin-3-yl]oxy-9H-thioxanthen-4-yl]-6-morpholin-4-ylpyran-4-one
    Show/Hide
Canonical SMILES
FC(F)CN1CC(C1)Oc1ccc2Sc3c(Cc2c1)cccc3-c1cc(=O)cc(o1)N1CCOCC1
    Show/Hide
Compound Formula C27H26F2N2O4S
Compound Structure
Protein Name
Serine-protein kinase ATM
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13315
Gene Name
ATM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM