Brief Information of the Compound and Protein
Compound Name
5-((4-((1r,4r)-4-hydroxy-4-(3-(trifluoromethyl)phenyl)cyclohexyl)piperazin-1-yl)methyl)pyridin-2(1H)-one
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Canonical SMILES
O=c1ccc(CN2CCN([C@H]3CC[C@@](O)(c4cccc(C(F)(F)F)c4)CC3)CC2)c[nH]1
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Compound Formula C23H28F3N3O2
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 5
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q9NQA5
Gene Name
TRPV5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS