Brief Information of the Compound and Protein
Compound Name
1-[(2S)-2-(cyclobutylmethoxy)propyl]-3-[4-methyl-5-(2-pyridin-4-ylethynyl)-1,3-thiazol-2-yl]urea
    Show/Hide
PubChem ID
CID: 59615757
Canonical SMILES
C[C@@H](CNC(=O)Nc1nc(C)c(s1)C#Cc1ccncc1)OCC1CCC1
    Show/Hide
Compound Formula C20H24N4O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 14 nM