Brief Information of the Compound and Protein
Compound Name
1-[2-(cyclopropylmethoxy)ethyl]-3-[4-methyl-5-[2-[6-(trifluoromethyl)pyridin-3-yl]ethynyl]-1,3-thiazol-2-yl]urea
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Canonical SMILES
Cc1nc(NC(=O)NCCOCC2CC2)sc1C#Cc1ccc(nc1)C(F)(F)F
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Compound Formula C19H19F3N4O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 52 nM