Brief Information of the Compound and Protein
Compound Name
1-[(2S)-2-(cyclopropylmethoxy)propyl]-3-[5-[2-(5,6-dimethylpyridin-3-yl)ethynyl]-4-methyl-1,3-thiazol-2-yl]urea
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Canonical SMILES
C[C@@H](CNC(=O)Nc1nc(C)c(s1)C#Cc1cnc(C)c(C)c1)OCC1CC1
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Compound Formula C21H26N4O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3 nM