Brief Information of the Compound and Protein
Compound Name
1-[2-[1-(2,2-difluoroethyl)imidazol-4-yl]ethyl]-3-[4-methyl-5-(2-pyridin-3-ylethynyl)-1,3-thiazol-2-yl]urea
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PubChem ID
CID: 49847093
SID: 104175310
Canonical SMILES
Cc1nc(NC(=O)NCCc2cn(CC(F)F)cn2)sc1C#Cc1cccnc1
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Compound Formula C19H18F2N6OS
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4 nM