Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(4S)-8-[5-[(6R)-6-amino-1,4-oxazepan-4-yl]-3-methylpyridin-2-yl]-4-methyl-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-2-deuterioquinoline-8-carbonitrile
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Canonical SMILES
[2H]c1ccc2c(ccc(C#N)c2n1)N1C[C@H](C)N2CCN(CC2C1)c1ncc(cc1C)N1CCOC[C@H](N)C1
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Compound Formula C29H36N8O
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000381 HEK-Blue hTLR8
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6 nM
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