Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(4R,9aR)-8-[5-(6-amino-2-azaspiro[3.3]heptan-2-yl)-3-methylpyridin-2-yl]-4-methyl-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-2-deuterioquinoline-8-carbonitrile
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 PubChem ID
CID: 155191967
Canonical SMILES
[2H]c1ccc2c(ccc(C#N)c2n1)N1C[C@@H](C)N2CCN(C[C@H]2C1)c1ncc(cc1C)N1CC2(CC(N)C2)C1
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Compound Formula C30H36N8
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 9
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR96
Gene Name
TLR9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000685 HEK-Blue hTLR9
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 81 nM
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