Brief Information of the Compound and Protein
Compound Name
(S)-4-Amino-5-((3-(7-fluoro-5-oxo-1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-4(5H)-yl)propyl)-amino)-5-oxopentanoic Acid
    Show/Hide
Canonical SMILES
N[C@@H](CCC(=O)O)C(=O)NCCCn1c(=O)c2cc(F)ccc2n2c(=S)[nH]nc12
    Show/Hide
Compound Formula C17H19FN6O4S
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 12650 nM
   TI
   LI
   LO
   TS