Brief Information of the Compound and Protein
Compound Name
4-(cyclopropylmethyl)-7-fluoro-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one
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Canonical SMILES
Fc1ccc2c(c1)c(=O)n(CC1CC1)c1n[nH]c(=S)n21
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Compound Formula C13H11FN4OS
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 770 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 770 nM