Brief Information of the Compound and Protein
Compound Name
tert-butyl 4-[2-(7-fluoro-5-oxo-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-4-yl)ethyl]piperazine-1-carboxylate
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Canonical SMILES
CC(C)(C)OC(=O)N1CCN(CCn2c3n[nH]c(=S)n3c3ccc(F)cc3c2=O)CC1
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Compound Formula C20H25FN6O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 1840 nM
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