Brief Information of the Compound and Protein
Compound Name
 Compound Info 
AG-014699
    Show/Hide
 PubChem ID
CID: 9931954
SID: 16463842
Canonical SMILES
CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
    Show/Hide
Compound Formula C19H18FN3O
Compound Structure
Protein Name
 Protein Info 
Poly [ADP-ribose] polymerase 2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q9UGN5
Gene Name
PARP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 0.8 nM
   TI
   LI
   LO
   TS
2
Ki = 0.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.4 nM
2 IC50 = 0.5 nM
3 IC50 = 1.5 nM
4 IC50 = 38.9 nM
5 Kd = 26 nM