Brief Information of the Compound and Protein
Compound Name
 Compound Info 
AG-014699
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 PubChem ID
CID: 9931954
SID: 16463842
Canonical SMILES
CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
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Compound Formula C19H18FN3O
Compound Structure
Protein Name
 Protein Info 
Poly [ADP-ribose] polymerase 1
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P09874
Gene Name
PARP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
2
Ki = 1.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.8 nM
2 IC50 = 0.8044 nM
3 IC50 = 1.7 nM
4 IC50 = 1.98 nM
5 IC50 = 4.7 nM
6 IC50 = 14.4 nM
7 IC50 > 500 nM
8 Kd = 3.2 nM
9 Ki = 1.4 nM