Brief Information of the Compound and Protein
Compound Name
Glpg-1205
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PubChem ID
CID: 71616860
Canonical SMILES
O=c1nc(OC[C@@H]2COCCO2)cc2-c3ccc(cc3CCn12)C#CC1CC1
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Compound Formula C22H22N2O4
Compound Structure
Protein Name
G-protein coupled receptor 84
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
Q9NQS5
Gene Name
GPR84
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  8
1
EC50 = 611 nM
   TI
   LI
   LO
   TS
2
EC50 = 655 nM
   TI
   LI
   LO
   TS
3
EC50 = 2918 nM
   TI
   LI
   LO
   TS
4
EC50 = 22100 nM
   TI
   LI
   LO
   TS
5
EC50 = 48600 nM
   TI
   LI
   LO
   TS
6
EC50 = 92400 nM
   TI
   LI
   LO
   TS
7
IC50 = 58 nM
   TI
   LI
   LO
   TS
8
IC50 = 112 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293 Homo sapiens (Human)  1
1
Ki = 30.2 nM
   TI
   LI
   LO
   TS