Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[6-chloro-3-[(2,5-difluorophenyl)sulfonylamino]-2-fluorophenyl]-6-methyl-4-[[(3S)-piperidin-3-yl]amino]quinazoline-8-carboxamide
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Canonical SMILES
Cc1cc(C(=O)Nc2c(Cl)ccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c2ncnc(N[C@H]3CCCNC3)c2c1
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Compound Formula C27H24ClF3N6O3S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase/endoribonuclease IRE1
Protein Classification
Enzyme
Uniprot ID
O75460
Gene Name
ERN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9900 nM