Brief Information of the Compound and Protein
Compound Name
1-(3-methoxyphenyl)-N-[2,3,6-trifluoro-4-[2-[[(3S,5S)-5-fluoropiperidin-3-yl]amino]-7-oxo-8-propan-2-ylpyrido[2,3-d]pyrimidin-6-yl]phenyl]methanesulfonamide
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PubChem ID
CID: 153634506
Canonical SMILES
COc1cccc(CS(=O)(=O)Nc2c(F)cc(c(F)c2F)-c2cc3cnc(N[C@@H]4CNC[C@@H](F)C4)nc3n(C(C)C)c2=O)c1
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Compound Formula C29H30F4N6O4S
Compound Structure
Protein Name
Serine/threonine-protein kinase/endoribonuclease IRE1
Protein Classification
Enzyme
Uniprot ID
O75460
Gene Name
ERN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.11 nM
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