Brief Information of the Compound and Protein
Compound Name
7-[(3S,4R)-1-(4-tert-butylpyridin-2-yl)-4-methylpiperidin-3-yl]-5-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine
    Show/Hide
PubChem ID
CID: 146369762
Canonical SMILES
C[C@@H]1CCN(C[C@H]1c1cc(nc2ncnn12)C(F)F)c1cc(ccn1)C(C)(C)C
    Show/Hide
Compound Formula C21H26F2N6
Compound Structure
Protein Name
cGMP-dependent 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 2
>
Phosphodiesterase 2A
Uniprot ID
O00408
Gene Name
PDE2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 155 nM
   TI
   LI
   LO
   TS